Saukewa: GDC6036-Atropisomer

Sunan Sinadari:

2-Propen-1-daya, 1-[(3S) -4-[7-[6-amino-4-methyl-3- (trifluoromethyl) -2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S) -1-methyl-2-pyrrolidinyl] methoxy] -4-quinazolinyl] -3-methyl-1-piperazinyl] -

Lambar SMILES:

C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F)=C(F) )C3=NC(OC[C@H]5N(C)CCC5=N2)CC1)=O

Lambar InChi:

InChi=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33) 34) 15 (2) 11-20 (35) 36-2 6)24 (31)25 (18)37-28 (38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6- 10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

InChi Key:

ZRBPIAWWRPFDPY-IRXDYDNUSA-N

Mabuɗin kalma:

2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8;GDC6036 atropisomers; GDC-6036; GDC 6036; Saukewa: GDC6036

Solubility: 

Ajiya:Dry, duhu kuma a 0 - 4 C na gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru).

Bayani:

GDC6036 anti rotation isomer ya ƙunshi nau'ikan GDC6036 isomers anti rotation iri biyu. GDC-6036, Wanda kuma aka sani da RG6330, abu ne na baka, mai inganci, kuma mai hanawa KRAS G12C.

Saukewa: KRAS G12C