Chenodeoxycholic acid

Sunan Sinadari:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a] phenanthren-17-yl pentanoic acid

Lambar SMILES:

C[C@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@] 4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H]) CC[C@]12C)CCC(O)=O

Lambar InChi:

InChi=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16 (25) 12-15 (23)13 -20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+ ,20-,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Mabuɗin kalma:

474-25-9, CAS: 474-25-9, CAS: 474-25-9, Chenodeoxycholic Acid, Anthropodeoxycholic acid, Anthropodesoxycholic acid, CCRIS 2195, Chendol, chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Solubility:Mai narkewa a cikin DMSO, ba cikin ruwa ba

Ajiya:Dry, duhu kuma a 0 - 4 C na gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru)

Bayani:

Chenodiol, wanda kuma aka sani da Chenodeoxycholic Acid da chenocholic acid, bile acid ne. Yana faruwa a matsayin wani abu mai farin crystalline wanda ba ya narkewa a cikin ruwa amma mai narkewa a cikin barasa da acetic acid, tare da narkewa a 165-167 ° C. Gishiri na wannan acid carboxylic ana kiransa chenodeoxycholates. An yi amfani da Chenodeoxycholic acid azaman magani don narkar da gallstones. Chenodeoxycholic acid za a iya amfani dashi a cikin maganin cerebrotendineous xanthomatosis. Kamfanin fasahar kere-kere na Australiya Giaconda ya gwada maganin cutar Hepatitis C wanda ya hada chenodeoxycholic acid da bezafibrate.

Manufa: Mai karɓar mai karɓar nukiliya FXR