BI-3812

Sunan Sinadari:

1- (5-Chloro-4- ((8-methoxy-1-methyl-3- (2- (methylamino)) -2-oxoethoxy-2-oxo-1,2-dihydroquinolin-6-yl) amino) pyrimidin -2-yl) -N, N-dimethylpiperidine-4-carboxamide

Lambar SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=O=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Lambar InChi:

InChi=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18 27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1- 5H3, (H,28,35)(H,29,30,31)

InChi Key:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Mabuɗin kalma:

BI-3812; BI 3812; BI3812

Solubility: 

Ajiya: 

Bayani:

BI-3812 shine mai hanawa mai ƙarfi na hulɗar yankin BTB / POZ na BCL6 tare da masu haɗin gwiwa da yawa. Yana aiki ta hanyar hana BCL6 :: Co-repressor hadaddun samuwar.

Saukewa: BCL6