BAY-299
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 500 |
| 500mg | A Stock | 800 |
| 1g | A Stock | 1200 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
2- (2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimizol-5-yl) -6- (3-hydroxypropyl) -1H-benz [de] isoquinoline-1,3 ( 2H) - wani
Lambar SMILES:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3=O)C5=C1C=CC=C5C2=O
Lambar InChi:
InChi=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8- 4-7-16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6, 11H2,1-3H3
InChi Key:
OFWWWKWUCDUISA-UHFFFAOYSA-N
Mabuɗin kalma:
BAY-299, BAY 299, BAY299, 2080306-23-4
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
BAY-299 shine mai hanawa mai ƙarfi da zaɓi na bromodomain da PHD mai ɗauke da yatsa (BRPF) furotin iyali BRD1 (IC50 = 6 nM), wanda kuma aka sani da BRPF2, da kuma na biyu bromodomain na ƙaddamar da fa'idar TFIID subnits 1 (TAF1; IC50) = 13 nM).1 BAY-299 shine> 30-ninka zaɓe akan BRPF1, BRPF3, BRD9, da ATAD2 kuma shine> zaɓin ninka 300 akan BRD4.
Saukewa: BRPF