BAR-502

Sunan Sinadari:

(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R) -6-ethyl-17-((R) -4-hydroxybutan-2-yl)-10,13-dimethylhexadecahydro-1H- cyclopenta [a] phenanthrene-3,7-diol

Lambar SMILES:

O[C@@H]1CC[C@]2(C)[C@@]3([H]) CC[C@] 4(C)[C@@H]([C@@H]( CCO)C) CC[C@@]4([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]2([H]) ]) C1

Lambar InChi:

InChi=1S/C25H44O3/c1-5-17-21-14-16(27)8-11-25(21,4)20-9-12-24(3)18(15(2)10-13- 26)6-7-19(24)22(20)23(17)28/h15-23,26-28H,5-14H2,1-4H3/t15-,16-,17-,18-,19+ ,20+,21+,22+,23-,24-,25-/m1/s1

InChi Key:

HYCMOIGNYNCMRH-APIYUPOTSA-N

Mabuɗin kalma:

1612191-86-2;CAS:1612191-86-2;CAS:1612191-86-2;BAR-502;BAR 502;BAR502

Solubility:Mai narkewa a cikin DMSO

Ajiya:0 - 4 C na gajeren lokaci (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni).

Bayani:

BAR502 mai dual agonist na FXR da GPBAR1.

Manufa: agonists biyu na FXR da GPBAR1