Sildenafil Citrate

Magaca Kiimikada:

5- (2-ethoxy-5- ((4-methylpiperazin-1-yl) sulfonyl) phenyl) -1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo [4,3-d] pyrimidin- 7-hal 2-hydroxypropane-1,2,3-tricarboxylate

Koodhka dhoola cadeynta:

"CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)CC(C(=O)O )C(CC(=O)O)(C(=O)O"

Koodhka InChi:

InChi=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-) 18 (16)32-6-2)33(30,31)28-12-10-26 (3)11-13-28;7-3 (8)1-6(13,5 (11)12) 2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)( H,9,10)(H,11,12)

Furaha InChi:

DEIYFTQMQPDXOT-UHFFFAOYSA-N

Ereyga muhiimka ah:

Sildenafil Citrate; UK 92480-10; UK-92,480-10; Revatio; VIAGRA; 171599-83-0;CAS:171599-83-0；CAS

Xalka:Ku milmay DMSO

Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)

Sharaxaad:

Sildenafil, Citrate waa nooc citrate ah oo Sildenafil ah. Sildenafil waa xakameyn door ah oo PDE5 ah (nooca 5 cGMP phosphodiesterase) kaas oo kicinaya hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). Sida PDE5 inhibitor ah, Sildenafil ayaa lagu soo warramey inuu kor u qaadayo neuro-, synapto- iyo angiogenesis ee moodooyinka jiirka ee istaroogga iyo sidoo kale waxaa lagu soo waramayaa inuu yahay vasodilator khafiif ah. Sildenafil ayaa sidoo kale la muujiyay si looga hortago indomethacin ay keento boogaha yaryar ee mindhicirka iyada oo loo marayo habka NO/cGMP-ku-tiirsanaanta.

Ujeedka: PDE5