Resmetirom

Magaca Kiimikada:

Resmetirom

Koodhka dhoola cadeynta:

N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O

Koodhka InChi:

InChi=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(4-11) 14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27, 28)

Furaha InChi:

FDBYIYFVSAHJLY-UHFFFAOYSA-N

Ereyga muhiimka ah:

MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom

Xalka:Ku milmay DMSO, oo aan ku milmin biyaha

Kaydinta:0 - 4 C muddo gaaban (maalmo ilaa toddobaadyo), ama -20 C muddo dheer (bilo)

Sharaxaad:

Resmetirom, oo sidoo kale loo yaqaan MGL-3196, waa mid awood leh oo aadka u xulashada hoormoonka tayroodhka receptor β agonist ee tijaabooyinka bukaan-socodka ee daaweynta dyslipidemia. Saamaynta faa'iidada leh ee hoormoonka tayroodhka (TH) ee heerarka dufanka ayaa ugu horreyntii sabab u ah ficilkeeda hoormoonka tayroodhka β (THR-β) ee beerka, halka saameynaha xun, oo ay ku jiraan saameynta wadnaha, ay dhexdhexaadiyaan hormoonka tayroodhka α (THR) -α).

Ujeedka: THR-β