Ingliforib
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide
Koodhka dhoola cadeynta:
O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O
Koodhka InChi:
InChi=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13)21 (30)23(3 2)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31 )/t17-,19-,20+,21+/m0/s1
Furaha InChi:
GVDRRZOORHCTAN-MJUUVYJYSA-N
Ereyga muhiimka ah:
Ingliforib; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296
Xalka:DMSO
Kaydinta:
Sharaxaad:
Ingliforib, oo sidoo kale loo yaqaan CP-368296, waa glycogen phosphorylase inhibitor ah oo cusub. Ingliforib waxay leedahay astaamo ka hortag ah hyperglycemic iyo wadnaha. Ingliforib waxay xakameysaa glycogen phosphorylase, enzyme-ka xaddidaya heerka glycogenolysis, taas oo ka hortagaysa sii deynta glucose-1 fosfate ka soo baxa glycogen molecule ee beerka. Wakiilkani wuxuu sidoo kale xannibaa glycogen fosforylase ee muruqa wadnaha wuxuuna ka ilaalin karaa wadnaha dhaawaca ischemic myocardial isagoo ilaalinaya maadada glycogen iyo hagaajinta isku dhafka glycolytic-oxidative
Bartilmaameedka: phosphorylase glycogen