Ingliforib

Ingliforib
  • Magaca:Ingliforib
  • Lambarka buugga:CPD2802
  • Lambarka CAS:186392-65-4
  • Miisaanka Molecular:457.91
  • Foomka Kiimikada:C23H24ClN3O5
  • Cilmi-baaris cilmiyeed oo keliya, maaha bukaannada.

    Faahfaahinta Alaabta

    Tags Product

    Cabbirka Xidhmada Helitaanka Qiimaha (USD)

    Magaca Kiimikada:

    5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide

    Koodhka dhoola cadeynta:

    O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O

    Koodhka InChi:

    InChi=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13)21 (30)23(3 2)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31 )/t17-,19-,20+,21+/m0/s1

    Furaha InChi:

    GVDRRZOORHCTAN-MJUUVYJYSA-N

    Ereyga muhiimka ah:

    Ingliforib; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296

    Xalka:DMSO

    Kaydinta: 

    Sharaxaad:

    Ingliforib, oo sidoo kale loo yaqaan CP-368296, waa glycogen phosphorylase inhibitor ah oo cusub. Ingliforib waxay leedahay astaamo ka hortag ah hyperglycemic iyo wadnaha. Ingliforib waxay xakameysaa glycogen phosphorylase, enzyme-ka xaddidaya heerka glycogenolysis, taas oo ka hortagaysa sii deynta glucose-1 fosfate ka soo baxa glycogen molecule ee beerka. Wakiilkani wuxuu sidoo kale xannibaa glycogen fosforylase ee muruqa wadnaha wuxuuna ka ilaalin karaa wadnaha dhaawaca ischemic myocardial isagoo ilaalinaya maadada glycogen iyo hagaajinta isku dhafka glycolytic-oxidative

    Bartilmaameedka: phosphorylase glycogen


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