GDC6036;GDC6036 atropisomers

Magaca Kiimikada:

2-Propen-1-hal, 1-[(3S) -4-[7-[6-amino-4-methyl-3-(trifluoromethyl) -2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S)-1-methyl-2-pyrrolidinyl] methoxy] -4-quinazolinyl] -3-methyl-1-piperazinyl] -

Koodhka dhoola cadeynta:

C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F) )C3=NC(OC[C@H]5N(C)CCC5=N2)CC1=O

Koodhka InChi:

InChi=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32, 33)34) 15 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

Furaha InChi:

ZRBPIAWWRPFDPY-IRXDYDNUSA-N

Ereyga muhiimka ah:

2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8;GDC6036 atropisomers; GDC-6036; GDC 6036; GDC6036

Xalka: 

Kaydinta:Qalalan, madow iyo 0 - 4 C muddo gaaban (maalmo ilaa toddobaadyo) ama -20 C muddada dheer (bilo ilaa sanado).

Sharaxaad:

GDC6036 isomer rotation anti rotation wuxuu ka kooban yahay laba nooc oo GDC6036 isomers rotation anti rotation ah. GDC-6036, Sidoo kale loo yaqaan RG6330, waa afka laga heli karo, aad u hufan, iyo xakameynta KRAS G12C.

Ujeedka: KRAS G12C