Etericoxib

Magaca Kiimikada:

5-Chloro-6'-methyl-3-[4-(methylsulfonyl) phenyl] -2,3'-bipyridine

Koodhka dhoola cadeynta:

O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

Koodhka InChi:

InChi=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-) 13)24 (2,22)23/h3-11H,1-2H3

Furaha InChi:

MNJVRJDLRVPLFE-UHFFFAOYSA-N

Ereyga muhiimka ah:

Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

Xalka:Ku milmay DMSO

Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)

Sharaxaad:

Etoricoxib waa daawada synthetic, nonsteroid anti-inflammatory (NSAID) oo leh daawoyinka antipyretic, xanuunka, iyo sifooyinka antineoplastic ee suurtagalka ah. Etoricoxib waxay si gaar ah ugu xidhan tahay oo u joojisaa enzyme cyclooxygenase-2 (COX-2), taasoo keentay in la joojiyo beddelka aashitada arachidonic ee prostaglandins. Joojinta COX-2 waxay keeni kartaa apoptosis waxayna joojisaa kororka unugyada burooyinka iyo angiogenesis.

Ujeedka: COX-2