Chenodeoxycholic acid

Magaca Kiimikada:

(R)-4-(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a] phenanthren-17-yl )pentanoic acid

Koodhka dhoola cadeynta:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Koodhka InChi:

InChi=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Furaha InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Ereyga muhiimka ah:

474-25-9, CAS: 474-25-9, CAS: 474-25-9, Chenodeoxycholic Acid, Anthropodeoxycholic acid, Anthropodesoxycholic acid, CCRIS 2195, Chendol, chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Xalka:Ku milmay DMSO, oo aan ku milmin biyaha

Kaydinta:Qalalan, madow iyo 0 - 4 C muddo gaaban (maalmo ilaa toddobaadyo) ama -20 C muddo dheer (bilo ilaa sanado)

Sharaxaad:

Chenodiol, oo sidoo kale loo yaqaan Chenodeoxycholic Acid iyo chenocholic acid, waa bile acid. Waxay u dhacdaa sida walax crystalline cad oo aan biyo ku milmin laakiin ku milma khamriga iyo acetic acid, oo leh barta dhalaalaysa 165-167 ° C. Cusbada ka mid ah aashitada karboxilic waxaa loo yaqaan chenodeoxycholates. Chenodeoxycholic acid waxa loo isticmaalay daawayn ahaan si loo milo dhagaxa xameetida. Chenodeoxycholic acid waxaa loo isticmaali karaa daawaynta xanthomatosis cerebrotendineous. Shirkadda cilmiga bayoolajiga ee Australian Giaconda ayaa tijaabisay daawaynta infekshanka Cagaarshowga C kaas oo isku daray chenodeoxycholic acid iyo bezafibrate.

Bartilmaameedka: Qaboojiyaha nukliyeerka ee firfircoon ee FXR