BMS-955176
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
4-(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-(2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a -pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a ,13b-octadecahydro-1H-cyclopenta[a] chrysen-9-yl) benzoic acid
Koodhka dhoola cadeynta:
O=C(O)C1=CC=C(C2=CC[C@@]3(C)[C@@](C2(C)C)([H])CC[C@@]4(C) )[C@]5(C)CC[C@](CC[C@H]6C(C)=C)(NCCN(CC7)CCS7(=O)=O)[C@@]6([H) ])[C@@]5([H]) CC[C@]34[H])C=C1
Koodhka InChi:
InChi=1S/C42H62N2O4S/c1-28(2)31-14-19-42(43-22-23-44-24-26-49(47,48)27-25-44)21-20-40( 6)33(36(31)42)12-13-35-39(5)17-15-32(29-8-10-30(11-9-29)37(45)46)38(3, 4)34(39)16-18-41(35,40)7/h8-11,15,31,33-36,43H,1,12-14,16-27H2,2-7H3,(H,45) ,46)/t31-,33+,34-,35+,36+,39-,40+,41+,42-/m0/s1
Furaha InChi:
XDMUFNNPLXHNKA-ZTESCHFWSA-N
Ereyga muhiimka ah:
GSK3532795, GSK-3532795, GSK 3532795, BMS-955176, BMS 955176, BMS955176
Xalka:
Kaydinta:
Sharaxaad:
GSK3532795, oo sidoo kale loo yaqaan BMS-955176, waa mid awood leh, hadal ahaan firfircoon, jiilka labaad ee HIV-1 inhibitor maturation (MI) kaas oo u gudbay marxaladda IIb ee tijaabooyinka kiliinikada. GSK3532795 wuxuu isku daraa daboolka ballaaran ee fayraska polymorphic (EC50<15 nM dhanka guddi ka kooban polymorphisms-ka caadiga ah oo ka kooban 96.5% HIV-1 nooc ka mid ah fayraska B) oo leh astaan farmaajo oo wanaagsan oo noocyo hore ah.
Bartilmaameedka: HIV-1 xakameynta korriinka (MI)