diABZI STING agonist-1 (Tautomerism)

ରାସାୟନିକ ନାମ:

(E) -1 - ((E) -4 - ((E) -5-carbamoyl-2 - ((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl) imino) -7- (3- morpholinopropoxy) -2,3-dihydro-1H-benzo [d] imidazol-1-yl) କିନ୍ତୁ-2-en-1-yl) -2 - ((1-ethyl-3-methyl-1H-pyrazole-5-) କାର୍ବନିଲ୍) ଇମିନୋ) -7-ମିଥୋକ୍ସି-2,3-ଡିହାଇଡ୍ରୋ -1 ଏଚ୍-ବେନଜୋ [d] ଇମିଡାଜୋଲ -5-କାର୍ବକ୍ସାମାଇଡ୍ |

ସ୍ମାଇଲ୍ କୋଡ୍:

O = C (N) C1 = CC (N / C (N2C / C = C / CN3 / C) (NC4 = C3C (OCCCN5CCOCC5)) CC (C) = NN6CC) = O) = NC (C7 = CC (C) = NN7CC) = O) = C2C (OC) = C1

InChi କୋଡ୍:

InChI = 1S / C42H51N13O7 / c1-6-54-31 (19-25 (3) 49-54) 39 (58) 47-41-45-29-21-27 (37 (43) 56) 23-33 ( 60-5) 35 (29) 52 (41) 12-8-9-13-53-36-30 (46-42 (53) 48-40 (59) 32-20-26 (4) 50-55 ( 32) 7-2) 22-28 (38 (44) 57) 24-34 (36) 62-16-10-11-51-14-17-61-18-15-51 / h8-9,19- 24H, 6-7,10-18H2,1-5H3, (H2,43,56) (H2,44,57) (H, 45,47,58) (H, 46,48,59) / b9-8 +

InChi କି:

JGLMVXWAHNTPRF-CMDGGOBGSA-N |

କୀ ଶବ୍ଦ:

ସମାଧାନ: 

ସଂରକ୍ଷଣ: 

ବର୍ଣ୍ଣନା:

diABZI STING agonist-1 Tautomerism (ଯ ound ଗିକ 3) ହେଉଛି ଇଣ୍ଟରଫେରନ୍ ଜିନ୍ (STING) ରିସେପ୍ଟର ଆଗୋନିଷ୍ଟର ଏକ ମନୋନୀତ ଉତ୍ତେଜକ, ଯଥାକ୍ରମେ ମାନବ ଏବଂ ମାଉସ୍ ପାଇଁ EC50s 130, 186 nM |

ଲକ୍ଷ୍ୟ: STING