MDK7526 HCl

Anarana simika:

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

Kaody SMILES:

O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

InChi Code:

InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27)11-26(1 7)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28) ;1H/t16-,17+,19-;/m1./s1

InChi Key:

JYRTWGCWUBURGU-MSSRUXLCSA-N

Keyword:

MDK7526 HCl, Protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

Solubility:Mety levona amin'ny DMSO

fitahirizana:0 - 4°C mandritra ny fotoana fohy (andro na herinandro), na -20°C mandritra ny fotoana maharitra (volana).

Famaritana:

MDK7526, antsoina koa hoe VHL Ligand 1; Protein degrader 1, dia mpamono proteinina mahery sy mifantina. Ny MDK7526 dia manana CAS#1448297-52-6, ny sira HCl dia manana CAS#1448189-80-7. Ny MDK7526 dia mety ilaina amin'ny fanimbana kendrena ny androgen receptor. Ny MDK7526 dia mamehy ny receptor androgen toy ny androgen receptor apetraka eo akaikin'ny ligase ubiquitin mba hampisy degrdn. (sy inhibition) ny androgen receptor.

Tanjona: Androgen Receptor