TIAB SA-22379
Product Detail
Khoom cim npe
Pob Loj | Muaj | Nqe (USD) |
100 mg | Hauv Tshuag | 350 |
250 mg | Hauv Tshuag | 600 |
1g | Hauv Tshuag | 1200 |
Ntau qhov ntau thiab tsawg | Tau txais Quotes | Tau txais Quotes |
Lub npe tshuaj:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide
SMILES Code:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCCC5
InChi Code:
InChI = 1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21)) 29-26(22) hnub. 32) 28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28) ,31)(H,29,32)/b22-13+
InChi Key:
INQUULPXCZAKMS-LPYMAVHISA-N
Lo lus tseem ceeb:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solubility:Soluble hauv DMSO
Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli)
Nqe lus piav qhia:
DEL-22379 yog lub zog thiab xaiv ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization yam tsis muaj kev cuam tshuam ERK phosphorylation, forestalls tumorigenesis tsav los ntawm RAS-ERK txoj hauv kev oncogenes. Ze li ntawm 50% ntawm tib neeg malignancies nthuav tawm tsis tswj RAS-ERK signaling; inhibiting nws yog ib lub tswv yim siv tau rau kev cuam tshuam antineoplastic.
Hom phiaj: ERK