86-21-64556180 ib

TIAB SA-22379

TIAB SA-22379
  • Lub npe:TIAB SA-22379
  • Catalog No.:TIAB SA 3713
  • CAS Nr:.181223-80-3
  • Molecular Luj:444.55 ib
  • Tshuaj Formula:C26H28N4O3
  • Rau kev tshawb fawb tshawb fawb nkaus xwb, tsis yog rau cov neeg mob.

    Product Detail

    Khoom cim npe

    Pob Loj Muaj Nqe (USD)
    100 mg Hauv Tshuag 350
    250 mg Hauv Tshuag 600
    1g Hauv Tshuag 1200
    Ntau qhov ntau thiab tsawg Tau txais Quotes Tau txais Quotes

    Lub npe tshuaj:

    (Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide

    SMILES Code:

    O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCCC5

    InChi Code:

    InChI = 1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21)) 29-26(22) hnub. 32) 28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28) ,31)(H,29,32)/b22-13+

    InChi Key:

    INQUULPXCZAKMS-LPYMAVHISA-N

    Lo lus tseem ceeb:

    DEL-22379, DEL22379, DEL 22379, 181223-80-3

    Solubility:Soluble hauv DMSO

    Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli)

    Nqe lus piav qhia:

    DEL-22379 yog lub zog thiab xaiv ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization yam tsis muaj kev cuam tshuam ERK phosphorylation, forestalls tumorigenesis tsav los ntawm RAS-ERK txoj hauv kev oncogenes. Ze li ntawm 50% ntawm tib neeg malignancies nthuav tawm tsis tswj RAS-ERK signaling; inhibiting nws yog ib lub tswv yim siv tau rau kev cuam tshuam antineoplastic.

    Hom phiaj: ERK


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