Ciforadenant

Lub npe tshuaj:

(S)-7-(5-methylfuran-2-yl)-3-((6-((((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2 ,3]triazolo[4,5-d]pyrimidin-5-amine

SMILES Code:

NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1

InChi Code:

InChI = 1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3- 2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/t15- /m0/s1

InChi Key:

KURQKNMKCGYWRJ-HNNXBMFYSA-N

Lo lus tseem ceeb:

Ciforadenant, CPI-444, V81444, CPI 444, CPI 444

Solubility:Soluble hauv DMSO

Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli)

Nqe lus piav qhia:

CPI-444 yog ib qho muaj zog, hais lus muaj, xaiv antagonist ntawm adenosine A2A receptor uas tau raug pom zoo nyob rau hauv Ph 1/1b cov kev tshawb fawb hauv cov lus qhia tsis yog oncology.

Hom phiaj: Adenosine A2A