PEB-502

Lub npe tshuaj:

3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-((R)-4-hydroxybutan-2-yl)-10,13-dimethylhexadecahydro-1H- cyclopenta [a]phenanthrene-3,7-diol

SMILES Code:

O[C@@H]1CC[C@@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H]( CCO)C)[C@@]4([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]2([H ]) C1

InChi Code:

InChI = 1S/C25H44O3/c1-5-17-21-14-16(27)8-11-25(21,4)20-9-12-24(3)18(15(2)10-13- 26) 6-7-19(24) hnub. 22(20)23(17)28/h15-23,26-28H,5-14H2,1-4H3/t15-,16-,17-,18-,19+,20+,21+,22+, 23-,24-,25-/m1/s1

InChi Key:

HYCMOIGNYNCMRH-APIYUPOTSA-N

Lo lus tseem ceeb:

1612191-86-2; CAS: 1612191-86-2; CAS: 1612191-86-2; BAR-502; BAR 502; BAR502

Solubility:Soluble hauv DMSO

Cia:0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 C rau lub sijhawm ntev (hli).

Nqe lus piav qhia:

BAR502 yog dual agonist ntawm FXR thiab GPBAR1.

Lub Hom Phiaj: Ob chav agonists ntawm FXR thiab GPBAR1