Unesbulin dawb puag, PTC596

Lub npe tshuaj:

5-Fluoro-2-(6-fluoro-2-methyl-1H-benzo[d]imidazol-1-yl)-N4-(4-(trifluoromethyl)phenyl)pyrimidine-4,6-diamine

SMILES Code:

NC1=C(F)C(NC2=CC=C(C(F)(F)F)C=C2)=NC(N3C(C)=NC4=CC=C(F)C=C34)=N1

InChi Code:

InChI=1S/C19H13F5N6/c1-9-26-13-7-4-11(20)8-14(13)30(9)18-28-16(25)15( 21)17(29-18)27-12-5-2-10(3-6-12)19(22,23)24/h2-8H,1H3,(H3,25,27,28,29)

InChi Key:

TWLWOOPCEXYVBE-UHFFFAOYSA-N

Lo lus tseem ceeb:

1610964-64-1; CAS: 1610964-64-1; CAS: 1610964-64-1; Unesbulin dawb puag; PTC596; PTC-596; PTC 596

Solubility:Soluble hauv DMSO

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

Unesbulin (PTC596) yog ib qho kev hais lus zoo thiab xaiv B-cell tshwj xeeb Moroni nas leukemia virus integration site 1 (BMI-1) inhibitor.

Lub hom phiaj: BMI-1