SJ-01

Lub npe tshuaj:

(E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-ib

SMILES Code:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

InChi Code:

InChI = 1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChi Key:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Lo lus tseem ceeb:

20069-09-4; CAS: 20069-09-4; CAS: 20069-09-4; Piperlongumine; Piplatine.

Solubility:Soluble hauv DMSO

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

Piperlongumine , tseem hu ua Piplatine , yog ib qho tshuaj lom neeg lom neeg alkaloid / amide los ntawm peppers, xws li kua txob ntev (Piper longum L. - Piperaceae). Cov kua txob ntev yog ib qho ntawm feem ntau siv hauv cov tshuaj Ayurvedic, uas yog siv los kho ntau yam kab mob, nrog rau cov qog. Cov kev ua ub no ntawm cov tshuaj piplartine muaj xws li cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocistal kev ua ub no. Ntawm ntau yam tshuaj muaj txiaj ntsig ntawm piplartine, nws cov cuab yeej tiv thaiv kab mob yog qhov zoo tshaj plaws.

Lub Hom Phiaj: Piperlongumine yog ib qho alkaloid uas inhibits kev hloov pauv ntawm myofibroblasts los ntawm inhibiting erk1/2 signaling pathway