Sildenafil Citrate

Lub npe tshuaj:

5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin- 7-ib 2-hydroxypropane-1,2,3-tricarboxylate

SMILES Code:

"CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)CC(C(=O)O)O )C(CC(=O)O)(C(=O)O)O"

InChi Code:

InChI = 1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9- 18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12) 2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)( H, 9, 10) (H, 11, 12)

InChi Key:

DEIYFTQMQPDXOT-UHFFFAOYSA-N

Lo lus tseem ceeb:

Sildenafil Citrate; UK 92480-10; UK-92,480-10; Revatio; VIAGRA; 171599-83-0; CAS: 171599-83-0; CAS: 171599-83-0

Solubility:Soluble hauv DMSO

Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli)

Nqe lus piav qhia:

Sildenafil, Citrate yog ib daim ntawv citrate ntawm Sildenafil. Sildenafil yog ib qho kev xaiv inhibitor ntawm PDE5 (hom 5 cGMP phosphodiesterase) uas catalyzes hydrolysis ntawm 3',5'-cyclic guanosine monophosphate (cGMP). Raws li PDE5 inhibitor, Sildenafil tau raug tshaj tawm los txhim kho neuro-, synapto- thiab angiogenesis hauv cov qauv nas ntawm cov hlab ntsha thiab kuj tau tshaj tawm tias yog ib qho vasodilator me me. Sildenafil kuj tau pom tias tiv thaiv indomethacin-induced plab hnyuv ulceration los ntawm ib qho NO / cGMP- nyob ntawm tus txheej txheem.

Hom phiaj: PDE5