PAB-7455

Lub npe tshuaj:

N4-cyclopropyl-N2-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine

SMILES Code:

COC1=C(OC)C=CC(NC2=NC(NC3CC3))=C(C(F)(F)F)C=N2)=C1

InChi Code:

InChI = 1S/C16H17F3N4O2/c1-24-12-6-5-10(7-13(12)25-2)22-15-20-8-11(16(17,18)19)14(23- 15) 21-9-3-4-9/h5-9H, 3-4H2,1-2H3, (H2,20,21,22,23)

InChi Key:

BQROJYIEHOOQBY-UHFFFAOYSA-N

Lo lus tseem ceeb:

1884222-74-5 ; CAS : 1884222-74-5 ; CAS : 1884222-74-5 ; SBP-7455 ; SBP 7455 ; SBP 7455

Solubility:Soluble hauv DMSO

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

SBP-7455 yog ib qho ua tau zoo, muaj kev sib raug zoo siab, thiab qhov ncauj ua haujlwm dual ULK1 / ULK2 autophagy inhibitor.

Hom phiaj: ULK1 / ULK2