CAT # | Khoom npe | Kev piav qhia |
PEB 3218 | BMS-955176 | GSK3532795, tseem hu ua BMS-955176, yog lub zog, qhov ncauj nquag, thib ob tiam HIV-1 maturation inhibitor (MI) uas tau nce mus txog theem IIb kev sim tshuaj. GSK3532795 sib txuas dav dav ntawm cov kab mob polymorphic (EC50)<15 nM mus rau lub vaj huam sib luag ntawm cov neeg sawv cev ntawm ntau hom polymorphisms ntawm 96.5% HIV-1 subtype B tus kab mob) nrog rau cov tshuaj pharmacokinetic profile nyob rau hauv hom preclinical. |