CAT # | Khoom npe | Kev piav qhia |
PAB 100391 | SIB 394 | |
PIB 100390 | SHP389 (dawb puag) | |
PEB 3242 | RMC-4550 | RMC-4550 yog ib qho muaj zog thiab xaiv SHP2 inhibitor. RMC-4550 tau txheeb xyuas tias yog cov cuab yeej siv tau zoo los kawm lub luag haujlwm ntawm SHP2 hauv cov qog nqaij hlav, ob qho tib si hauv vitro thiab hauv vivo hauv cov nas. SHP2 yog qhov sib koom ua ke ntawm qhov taw qhia thiab inhibition ntawm SHP2 yog qhov zoo hauv kev tsom mus rau ob qho tib si ntws (RTK-tsav) thiab qis qis (RAS-GTP nyob ntawm) kev hloov pauv hauv RAS-MAPK txoj hauv kev. |