Obicetrapib AMG-899; TA-8995

Lub npe tshuaj:

4-((2-((3,5-bis(trifluoromethyl)benzyl)((2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin -4-yl)amino)pyrimidin-5-yl)oxy)butanoic acid

SMILES Code:

O=C(O)CCOC1=CN=C(N(CC2=CC(C(F)(F)F))=CC(C(F)(F)F)=C2)[C@H]3C[C] @@H](CC)N(C(OCC)=O)C4=C3C=C(C(F)(F)F)C=C4)N=C1

InChi Code:

InChI=1S/C32H31F9N4O5/c1-3-22-14-26(24-13-19(30(33,34)35)7-8- 25(24)45(22)29(48)49-4-2)44(28-42-15-23(16-43-28)50-9-5-6-27( 46) 47) 17-18-10-20(31(36,37)38)12-21(11-18)32(39,40)41/h7-8,10 -13,15-16,22,26H,3-6,9,14,17H2,1-2H3,(H,46,47)/t22-,26+/m1/s1

InChi Key:

NRWORBQAOQVYBJ-GJZUVCINSA-N

Lo lus tseem ceeb:

866399-87-3; CAS: 866399-87-3; CAS: 866399-87-3; Obicetrapib; AMG-899; AMG 899; AMG899; TA-8995; TA8995; TA 8995; DEZ-001; DEZ 001; TIAB SA 001

Solubility:Soluble hauv DMSO

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

Obicetrapib, tseem hu ua AMG-899, TA-8995, thiab DEX-001, yog cov roj cholesterol hloov pauv cov protein (CETP) inhibitor.

Hom phiaj: CETP