NST-628

Lub npe tshuaj:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-ib

SMILES Code:

FC1=C(OC2=CC=C(C(C))=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2) N = CC = C1

InChi Code:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12) 10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26) , 28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Lo lus tseem ceeb:

3002056-30-3; CAS: 3002056-30-3; CAS: 3002056-30-3; NST-628; NST628; NST 628

Solubility: 

Cia:Qhuav, tsaus thiab ntawm 0 -4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

NST-628 yog MAPK txoj hauv kev molecular gel nrog ntshav-hlwb barrier permeability, uas tuaj yeem cuam tshuam RAF phosphorylation thiab MEK ua kom.

Hom phiaj: RAF phosphorylation thiab MEK