MDK7526 HCl

Lub npe tshuaj:

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

SMILES Code:

O=C([C@H]1N(C([C@@H](N)C(C)(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

InChi Code:

InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27) 11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,( H,24,28);1H/t16-,17+,19-;/m1./s1

InChi Key:

JYRTWGCWUBURGU-MSSRUXLCSA-N

Lo lus tseem ceeb:

MDK7526 HCl, Protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

Solubility:Soluble hauv DMSO

Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli).

Nqe lus piav qhia:

MDK7526, tseem hu ua VHL Ligand 1; Protein degrader 1, yog lub zog thiab xaiv cov protein degrader. MDK7526 muaj CAS # 1448297-52-6, HCl ntsev CAS # 1448189-80-7. MDK7526 muaj peev xwm pab tau rau lub hom phiaj degradation ntawm androgen receptor. MDK7526 khi androgen receptor xws li androgen receptor yog muab tso rau hauv qhov sib thooj rau ubiquitin ligase kom cuam tshuam degrdn. (thiab inhibition) ntawm androgen receptor.

Hom phiaj: Androgen Receptor