Ib, BI 853520

Lub npe tshuaj:

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl) benzamide

SMILES Code:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3) C = C2F

InChi Code:

InChI = 1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

InChi Key:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Lo lus tseem ceeb:

1227948-82-4; CAS: 1227948-82-4; CAS: 1227948-82-4; Isebemtinib; BI 853520

Solubility:Soluble hauv DMSO, tsis nyob hauv dej

Cia:0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 C rau lub sijhawm ntev (hli).

Nqe lus piav qhia:

Ifebemtinib (BI 853520) yog ib qho muaj zog inhibitor ntawm focal adhesion kinase (FAK) nrog rau qhov ncauj.

Hom phiaj: FAK Strong Inhibitor