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Divarasib, GDC 6036

Divarasib, GDC 6036
  • Lub npe:1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-ib
  • Catalog No.:PAB 112857
  • CAS Nr.:2417987-45-0
  • Molecular Luj:622.06 ib
  • Tshuaj Formula:C29 H32 Cl F4 N7 O2
  • Rau kev tshawb fawb tshawb fawb nkaus xwb, tsis yog rau cov neeg mob.

    Product Detail

    Khoom cim npe

    Pob Loj Muaj Nqe (USD)
    0.1g ua Hauv Tshuag 550
    0,5g ua Hauv Tshuag 860 ua
    1G Hauv Tshuag 1250

    Lub npe tshuaj:

    1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-ib

    SMILES Code:

    NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F

    InChi Code:

    InChI = 1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32), 33) 34) 15(2) 11-20 (35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H , 1,6-10,13-14H2,2-4H3,(H2,35,36)

    InChi Key:

    ZRBPIAWRPFDPY-UHFFFAOYSA-N

    Lo lus tseem ceeb:

    2417987-45-0; CAS: 2417987-45-0; CAS: 2417987-45-0; Divarasib; GDC 6036 Nr.

    Solubility:Solubility Yuav txiav txim siab

    Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

    Nqe lus piav qhia:

    Divarasib (GDC-6036) yog KRAS G12C inhibitor nrog rau qhov ncauj bioavailability thiab xaiv.

    Hom phiaj: KRAS G12C inhibitor




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