Chenodeoxycholic Acid

Lub npe tshuaj:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl (Pentanoic acid).

SMILES Code:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CC(O)=O

InChi Code:

InChI = 1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Lo lus tseem ceeb:

474-25-9, CAS: 474-25-9, CAS: 474-25-9, Chenodeoxycholic Acid, Anthropodesoxycholic acid, Anthropodesoxycholic acid, CCRIS 2195, Chendol, chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Solubility:Soluble hauv DMSO, tsis nyob hauv dej

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo)

Nqe lus piav qhia:

Chenodiol, tseem hu ua Chenodeoxycholic Acid thiab chenocholic acid, yog cov kua tsib acid. Nws tshwm sim raws li ib tug dawb crystalline khoom insoluble nyob rau hauv dej tab sis soluble nyob rau hauv cawv thiab acetic acid, nrog melting point ntawm 165-167 ° C. Cov ntsev ntawm cov carboxylic acid yog hu ua chenodeoxycholates. Chenodeoxycholic acid tau siv los ua kev kho mob kom yaj lub gallstones. Chenodeoxycholic acid tuaj yeem siv rau hauv kev kho mob cerebrotendineous xanthomatosis. Lub tuam txhab Australian biotechnology Giaconda tau sim tshuaj kho kab mob siab C uas ua ke nrog chenodeoxycholic acid nrog bezafibrate.

Lub Hom Phiaj: Ua kom muaj zog nuclear receptor FXR