ARS-1323-Alkyne

Lub npe tshuaj:

3-((4-(4-acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-2-yl)amino)-N-methyl-N- (prop-2-yn-1-yl) propanamide

SMILES Code:

O=C(N(C)CC#C)CCNC1=NC(N2CCN(C(C=C)=O)CC2)=C3C=C(Cl)C(C4=C(O)C=CC=C4F) =C(F)C3=N1

InChi Code:

InChI = 1S/C28H27ClF2N6O3/c1-4-11-35(3)22(40)9-10-32-28-33-26-17(27(34-28)37-14-12-36(13- 15-37) 21(39)5-2)16-18(29)23(25(26)31)24-19(30)7-6-8-20(24)38/h1,5-8,16,38H, 2,9-15H2,3H3,(H,32,33,34)

InChi Key:

FCCFZQSNDSLLMI-UHFFFAOYSA-N

Lo lus tseem ceeb:

2436544-27-1; CAS: 2436544-27-1; CAS: 2436544-27-1; ARS-1323-Alkyne; ARS1323-Alkyne; ARS 1323-Alkyne; ARS-1323 Alkyne

Solubility:Soluble hauv DMSO

Cia:Qhuav, tsaus thiab ntawm 0 - 4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

ARS-1323-alkyne, hloov-II hnab tshos (S-IIP) inhibitor

Hom phiaj: hloov-II hnab tshos (S-IIP)