Zasocitinib，NDI 034858

Chemical Name:

N-[(1R,2R)-2-methoxycyclobutyl]-7-(methylamino)-5-[(2-oxo[1(2H),2'-bipyridin]-3-yl)amino]-pyrazolo[1,5-a]pyrimidine-3-carboxamide

SMILES Code: 

O=C(C1=C2N=C(NC3=CC=CN(C4=NC=CC=C4)C3=O)C=C(NC)N2N=C1)N[C@H]5[C@H](OC)CC5

InChi Code:

InChI=1S/C23H24N8O3/c1-24-20-12-18(27-16-6-5-11-30(23(16)33)19-7-3-4-10-25-19)29-21-14(13-26-31(20)21)22(32)28-15-8-9-17(15)34-2/h3-7,10-13,15,17,24H,8-9H2,1-2H3,(H,27,29)(H,28,32)/t15-,17-/m1/s1

InChi Key:

BWINBHTTZLVXGT-NVXWUHKLSA-N

Keyword:

2272904-53-5；CAS:2272904-53-5；CAS：2272904-53-5；Zasocitinib；NDI 034858

Solubility: To be determined

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Zasocitinib (NDI-034858) 是一种 Tyk2 抑制剂，靶向 Tyk2 的 JH2 结构域，结合常数 Kd <200 pM。

Target: Tyk2 inhibitor