Verucerfont

Verucerfont
  • Name: Verucerfont; GSK561679; NBI77860
  • Catalog No.: CPDD1230
  • CAS No.: 885220-61-1
  • Molecular Weight: 406.49
  • Chemical Formula: C22H26N6O2
  • For scientific research only, not for patients.

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    100mg In Stock 700
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    Chemical Name:

    (S)-3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-(1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl)pyrazolo[1,5-a]pyrimidin-7-amine

    SMILES Code: 

    CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4

    InChi Code:

    InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1

    InChi Key:

    VKHVAUKFLBBZFJ-SFHVURJKSA-N

    Keyword:

    Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    "Verucerfont, also known as GSK561679 and NBI77860, is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism, as chronic stress is often a factor in both development of alcoholism and relapse in recovering alcoholics. It has shown promising results in animal studies but has not been tested in humans. "

    Target: CRF-1


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