Tuspetinib; HM43239

Tuspetinib; HM43239
  • Name: 5-chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)phenyl)-4-(6-methyl-1H-indol-3-yl)pyrimidin-2-amine
  • Catalog No.: CPDP801866
  • CAS No.: 2294874-49-8
  • Molecular Weight: 501.07
  • Chemical Formula: C29 H33 Cl N6
  • For scientific research only, not for patients.

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    Chemical Name:

    5-chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)phenyl)-4-(6-methyl-1H-indol-3-yl)pyrimidin-2-amine

    SMILES Code: 

    CC1C=CC2C(=CNC=2C=1)C1C(Cl)=CN=C(NC2C=C(C3CC3)C=C(CN3C[C@@H](C)N[C@@H](C)C3)C=2)N=1

    InChi Code:

    InChI=1S/C29H33ClN6/c1-17-4-7-24-25(12-31-27(24)8-17)28-26(30)13-32-29(35-28)34-23-10-20(9-22(11-23)21-5-6-21)16-36-14-18(2)33-19(3)15-36/h4,7-13,18-19,21,31,33H,5-6,14-16H2,1-3H3,(H,32,34,35)/t18-,19+

    InChi Key:

    FZLSDZZNPXXBBB-KDURUIRLSA-N

    Keyword:

    2294874-49-8;CAS:2294874-49-8;CAS:2294874-49-8; HM43239; HM 43239; HM-43239;Tuspetinib

    Solubility: DMSO : 125 mg/mL (249.47 mM; Need ultrasonic)

    Storage: 4°C, protect from light

    Description: 

    Tuspinib (HM43239) is a selective FLT3 inhibitor with oral activity.

    Target: FLT3




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