Ropotrectinib
Product Detail
Product Tags
| Pack Size | Availability | Price (USD) |
Chemical Name:
(7S,13R)-11-fluoro-6,7,13,14-tetrahydro-7,13-dimethyl-1,15-etheno-1H-pyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one
SMILES Code:
O=C1NC[C@H](C)OC2=CC=C(F)C=C2[C@@H](C)NC3=NC4=C1C=NN4C=C3
InChi Code:
InChI=1S/C18H18FN5O2/c1-10-8-20-18(25)14-9-21-24-6-5-16(23-17(14)24)22-11(2)13-7-12(19)3-4-15(13)26-10/h3-7,9-11H,8H2,1-2H3,(H,20,25)(H,22,23)/t10-,11+/m0/s1
InChi Key:
FIKPXCOQUIZNHB-WDEREUQCSA-N
Keyword:
1802220-02-5；CAS:1802220-02-5；CAS：1802220-02-5；Ropotrectinib；TPX-0005；TPX 0005；TPX0005
Solubility: Soluble in DMSO
Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Description:
Repotrecinib (TPX-0005) is an effective inhibitor of ROS1 (IC50=0.07 nM) and TRK (IC50=0.83/0.05/0.1 nM for TRKA/B/C).
Target: ROS1 and TRK inhibitors
