PI3K

CAT # Product Name Description
CPD1573 GDC-0077 GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity.
CPD1022 IPI-549 IPI549 is a potent and selective PI3Kγ Inhibitor with an IC50 of 16 nM.
CPDD3857 GDC-0326 GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 achieves a very high level of selectivity over other kinases. GDC-0326 has low plasma CL in human.
CPDB0202 AZD8186 AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential antineoplastic activity.
CPDB1536 PQR530 PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor.
CPDB1573 GDC-0077 GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms.

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