Ozanimod

Ozanimod
  • Name: Ozanimod, RPC1063
  • Catalog No.: CPD3744
  • CAS No.: 1306760-87-1
  • Molecular Weight: 404.46
  • Chemical Formula: C23H24N4O3
  • For scientific research only, not for patients.

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    Chemical Name:

    (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile

    SMILES Code: 

    N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

    InChi Code:

    InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3-4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3/t20-/m0/s1

    InChi Key:

    XRVDGNKRPOAQTN-FQEVSTJZSA-N

    Keyword:

    Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    Ozanimod is a selective, orally available modulator of the sphingosine-1-phosphate (S1P) receptors S1P1 and SIP5. It induces internalization of S1P1, decreases circulating B and CCR7(+) T lymphocytes, and reduces inflammation and disease parameters in three autoimmune disease models.1 Ozanimod is in clinical trials for relapsing multiple sclerosis and ulcerative colitis.

    Target: S1P


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