Tirabrutinib; ONO-4059

Chemical Name:

(R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one

SMILES Code: 

O=C1N(C2=CC=C(C=C2)OC3=CC=CC=C3)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5

InChi Code:

InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1

InChi Key:

SEJLPXCPMNSRAM-GOSISDBHSA-N

Keyword:

1351636-18-4；CAS：1351636-18-4；CAS:1351636-18-4；ONO4059；ONO 4059；ONO-4059；Tirabrutinib

Solubility: Soluble in DMSO

Storage: Store at -20°C

Description: 

Tirabrutinib (ONO-4059) is an orally effective, highly selective Bruton's Tyrosine Kinase (BTK) inhibitor.

Target: BTK