NST-628

Chemical Name:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

SMILES Code: 

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4=C2)N=CC=C1

InChi Code:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16(12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26,28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Keyword:

3002056-30-3；CAS：3002056-30-3；CAS:3002056-30-3；NST-628；NST628；NST 628

Solubility: 

Storage: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Description: 

NST-628 is a MAPK pathway molecular gel with blood-brain barrier permeability, which can inhibit RAF phosphorylation and MEK activation.

Target: RAF phosphorylation and MEK