NBI-921352
Product Detail
Product Tags
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Chemical Name:
Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3S)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-N-4-thiazolyl-
SMILES Code:
O=S(C1=CC(C)=C(N(C)[C@@H]2CN(CC3=CC=CC=C3)CC2)C=C1F)(NC4=CSC=N4)=O
InChi Code:
InChI=1S/C22H25FN4O2S2/c1-16-10-21(31(28,29)25-22-14-30-15-24-22)19(23)11-20(16)26(2)18-8-9-27(13-18)12-17-6-4-3-5-7-17/h3-7,10-11,14-15,18,25H,8-9,12-13H2,1-2H3/t18-/m0/s1
InChi Key:
UCSHINHOAVARGQ-SFHVURJKSA-N
Keyword:
2154406-04-7；CAS:2154406-04-7；CAS：2154406-04-7；NBI-921352; NBI921352; NBI 921352; XEN901; XEN 901; XEN-901
Solubility: To be determined
Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Description:
NBI-921352 is a potent, highly selective Nav1.6 sodium channel inhibitor being developed to treat pediatric patients with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) and other potential indications, including adult focal epilepsy.
Target: Efficient and highly selective Nav1.6 sodium channel inhibitor
