ML 265；CID44246499；NCGC 00186528；TEPP46

Chemical Name:

6-(3-aminobenzyl)-4-methyl-2-(methylsulfinyl)-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one

SMILES Code: 

O=C1C(N(C)C2=C3SC(S(C)=O)=C2)=C3C=NN1CC4=CC=CC(N)=C4

InChi Code:

InChI=1S/C17H16N4O2S2/c1-20-13-7-14(25(2)23)24-16(13)12-8-19-21(17(22)15(12)20)9-10-4-3-5-11(18)6-10/h3-8H,9,18H2,1-2H3

InChi Key:

ZWKJWVSEDISQIS-UHFFFAOYSA-N

Keyword:

1221186-53-3；CAS：1221186-53-3；CAS:1221186-53-3；ML265; ML-265; ML 265; CID44246499; CID-44246499; CID 44246499; NCGC00186528; NCGC 00186528; NCGC-00186528; TEPP46; TEPP 46; TEPP-46

Solubility: Soluble in DMSO, not in water

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Description: 

TEPP-46 (ML-265) is an effective and selective activator of pyruvate kinase M2 (PKM2).

Target: pyruvate kinase M2; PKM2