H3B-6527

H3B-6527
  • Name: H3B-6527
  • Catalog No.: CPD0999
  • CAS No.: 1702259-66-2
  • Molecular Weight: 629.54
  • Chemical Formula: C29H34Cl2N8O4
  • For scientific research only, not for patients.

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    Pack Size Availability Price (USD)
    100mg In stock 500
    500mg In stock 775
    1g In stock 1750
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    Chemical Name:

    N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide

    SMILES Code: 

    C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O

    InChi Code:

    InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)

    InChi Key:

    MBWRLLRCTIYXDW-UHFFFAOYSA-N

    Keyword:

    H3B-6527, H3B 6527, H3B6527, 1702259-66-2

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.

    Target: FGFR4




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