Ensifentrine; RPL 554; VMX 554

Ensifentrine; RPL 554; VMX 554
  • Name: N-(2-{(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl}ethyl)urea
  • Catalog No.: CPD100369
  • CAS No.: 1884461-72-6
  • Molecular Weight: 477.56
  • Chemical Formula: C26 H31 N5 O4
  • For scientific research only, not for patients.

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    Chemical Name:

    N-(2-{(2E)-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl}ethyl)urea

    SMILES Code: 

    O=C(N)NCCN1C(N(CCC2=C3C=C(OC)C(OC)=C2)C3=C/C1=NC4=C(C)C=C(C)C=C4C)=O

    InChi Code:

    InChI=1S/C26H31N5O4/c1-15-10-16(2)24(17(3)11-15)29-23-14-20-19-13-22(35-5)21(34-4)12-18(19)6-8-30(20)26(33)31(23)9-7-28-25(27)32/h10-14H,6-9H2,1-5H3,(H3,27,28,32)/b29-23+

    InChi Key:

    CSOBIBXVIYAXFM-BYNJWEBRSA-N

    Keyword:

    1884461-72-6;CAS:1884461-72-6;CAS:1884461-72-6;RPL 554;RPL-554;RPL554;VMX 554;VMX-554;VMX554;Ensifentrine

    Solubility: Soluble in DMSO

    Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

    Description: 

    Ensifentrine (RPL-554) is an inhaled, pioneering dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4.

    Target:  PDE3 and PDE4




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