Divarasib,GDC 6036

Divarasib,GDC 6036
  • Name: 1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
  • Catalog No.: CPD112857
  • CAS No.: 2417987-45-0
  • Molecular Weight: 622.06
  • Chemical Formula: C29 H32 Cl F4 N7 O2
  • For scientific research only, not for patients.

    Product Detail

    Product Tags

    Pack Size Availability Price (USD)
    0.1G In Stock 550
    0.5G In Stock 860
    1G In Stock 1250

    Chemical Name:

    1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

    SMILES Code: 

    NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F

    InChi Code:

    InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)

    InChi Key:

    ZRBPIAWWRPFDPY-UHFFFAOYSA-N

    Keyword:

    2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036

    Solubility: SolubilityTo be determined

    Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

    Description: 

    Divarasib (GDC-6036) is a KRAS G12C inhibitor with oral bioavailability and selectivity.

    Target: KRAS G12C inhibitor




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