Chenodeoxycholic Acid

Chemical Name:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

SMILES Code: 

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

InChi Code:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Keyword:

474-25-9，CAS:474-25-9，CAS：474-25-9，Chenodeoxycholic Acid， Anthropodeoxycholic acid，Anthropodesoxycholic acid，CCRIS 2195，Chendol，chenic acid; Chenix，Chenodeoxycholic acid， Chenodesoxycholic acid，Chenodiol，Gallodesoxycholic acid， NSC 657949， Xenbilox

Solubility: Soluble in DMSO, not in water

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Description: 

Chenodiol, also known as Chenodeoxycholic Acid and chenocholic acid, is a bile acid. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167 °C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid has been used as medical therapy to dissolve gallstones. Chenodeoxycholic acid can be used in the treatment of cerebrotendineous xanthomatosis. The Australian biotechnology company Giaconda has tested a treatment for Hepatitis C infection that combines chenodeoxycholic acid with bezafibrate.

Target: Activated nuclear receptor FXR