BEC HCl

Chemical Name:

(R)-2-amino-3-((2-boronoethyl)thio)propanoic acid hydrochloride

SMILES Code: 

N[C@@H](CSCCB(O)O)C(O)=O.[H]Cl

InChi Code:

InChI=1S/C5H12BNO4S.ClH/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8,9);1H/t4-;/m0./s1

InChi Key:

GHPYJLCQYMAXGG-WCCKRBBISA-N

Keyword:

BEC HCl, 222638-67-7

Solubility: Soluble in DMSO

Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months)

Description: 

BEC, also known as S-(2-boronoethyl)-L-cysteine, is an a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM (ph 7.5). BEC significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM. S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum.

Target: Arginase