AZD7507

AZD7507
  • Name: AZD7507
  • Catalog No.: CPD2026
  • CAS No.: 1041852-85-0
  • Molecular Weight: 454.2
  • Chemical Formula: C23H27FN6O3
  • For scientific research only, not for patients.

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    Chemical Name:

    4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide

    SMILES Code: 

    O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N

    InChi Code:

    InChI=1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9-10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4,11-13,31H,5-10H2,1-2H3,(H2,25,32)(H,26,27)

    InChi Key:

    CPDGCAFPSYOTGO-UHFFFAOYSA-N

    Keyword:

    AZD7507; AZD-7507; AZD 7507

    Solubility: DMSO

    Storage: 

    Description: 

    AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is considered a promising compound as it retained the desired potency and oral pharmacokinetic properties of AZ683. Moreover, in a telemetry study in dogs given a single oral dose, there was no cardiovascular toxicity, no elevation of troponin related to the treatment, and no alteration in the ECG.

    Target: CSF-1R


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