AZD-5305
Product Detail
Product Tags
Pack Size | Availability | Price (USD) |
10mg | In Stock | 290 |
100mg | In Stock | 650 |
1g | In Stock | 2100 |
Chemical Name:
5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylpicolinamide
SMILES Code:
O=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC
InChi Code:
InChI=1S/C22H26N6O2/c1-3-16-11-19-20(26-21(16)29)10-15(12-24-19)14-27-6-8-28(9-7-27)17-4-5-18(25-13-17)22(30)23-2/h4-5,10-13H,3,6-9,14H2,1-2H3,(H,23,30)(H,26,29)
InChi Key:
WQAVGRAETZEADU-UHFFFAOYSA-N
Keyword:
2589531-76-8;CAS:2589531-76-8;CAS:2589531-76-8;AZD5305; AZD-5305; AZD 5305
Solubility: To be determined
Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Description:
AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species.
Target: PARP inhibitor