AZD-5305

AZD-5305
  • Name: AZD-5305
  • Catalog No.: CPD108743
  • CAS No.: 2589531-76-8
  • Molecular Weight: 406.48
  • Chemical Formula: C22 H26 N6 O2
  • For scientific research only, not for patients.

    Product Detail

    Product Tags

    Pack Size Availability Price (USD)
    10mg In Stock 290
    100mg In Stock 650
    1g In Stock 2100

    Chemical Name:

    5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylpicolinamide

    SMILES Code: 

    O=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC

    InChi Code:

    InChI=1S/C22H26N6O2/c1-3-16-11-19-20(26-21(16)29)10-15(12-24-19)14-27-6-8-28(9-7-27)17-4-5-18(25-13-17)22(30)23-2/h4-5,10-13H,3,6-9,14H2,1-2H3,(H,23,30)(H,26,29)

    InChi Key:

    WQAVGRAETZEADU-UHFFFAOYSA-N

    Keyword:

    2589531-76-8;CAS:2589531-76-8;CAS:2589531-76-8;AZD5305; AZD-5305; AZD 5305

    Solubility: To be determined

    Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

    Description: 

    AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species.

    Target: PARP inhibitor




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