VU0448088 (ML253)

Chemical Name:

3-amino-5-chloro-4,6-dimethyl-N-(pyridin-4-ylmethyl)thieno[2,3-b]pyridine-2-carboxamide

SMILES Code: 

CC1=NC2=C(C(N)=C(S2)C(NCC3=CC=NC=C3)=O)C(C)=C1Cl

InChi Code:

InChI=1S/C16H15ClN4OS/c1-8-11-13(18)14(23-16(11)21-9(2)12(8)17)15(22)20-7-10-3-5-19-6-4-10/h3-6H,7,18H2,1-2H3,(H,20,22)

InChi Key:

XNCQMFVABACABG-UHFFFAOYSA-N

Keyword:

1417616-42-2；CAS：1417616-42-2；CAS:1417616-42-2；VU0448088；ML253；ML 253；ML-253

Solubility: 

Storage: 

Description: 

VU0448088 (ML253) is an effective positive allosteric modulator of tricyclic muscarinic acetylcholine receptor subtype 4 (M4) that can cross the blood-brain barrier.

Target: tricyclic muscarinic acetylcholine receptor subtype 4 (M4)