Lirafugratinib; RLY-4008

Chemical Name:

N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylprop-2-enamide

SMILES Code: 

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N=CN=C5N2C)C=C1)=O

InChi Code:

InChI=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26(23)36(24)4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2-4H3,(H,35,37)(H2,30,32,33)

InChi Key:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

Keyword:

2549174-42-5；CAS：2549174-42-5；CAS:2549174-42-5；Lirafugratinib; RLY-4008; RLY 4008; RLY4008

Solubility: 

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Lirafugratinib (RLY-4008) is an orally active, irreversible, and highly selective FGFR2 inhibitor.

Target: FGFR2